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Triethyl phosphonoacetate : ウィキペディア英語版
Triethyl phosphonoacetate

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Triethyl phosphonoacetate is a reagent for organic synthesis used in the Horner-Wadsworth-Emmons reaction (HWE) or the Horner-Emmons modification.
Triethyl phosphonoacetate can be added dropwise to sodium methoxide solution to prepare a phosphonate ylide. It has an acidic proton that can easily be abstracted by a weak base. When used in an HWE reaction with a carbonyl the resulting alkene formed is usually the ''E'' alkene, and is generated with excellent regioselectivity.〔DOI: 10.1021/jo00215a004〕
==References==



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